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- Collection: Outstanding Faculty Publications 2022
- Fresno State author is exactly "Cory L. Brooks"
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Crystal structure of a human MUC16 SEA domain reveals insight into the nature of the CA125 tumor marker
MUC16 is a membrane bound glycoprotein involved in the progression and metastasis of pancreatic and ovarian cancer. The protein is shed into the serum and the resulting cancer antigen 125 (CA125) can be detected by immunoassays. The CA125 epitope is…